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The preparation or 'preparo' of Vegetal begins with the harvest of the Mariri.
The Hoasca Project, carried out in 1993, studied a group of 15 users, each with more than 10 years of regular use of the Vegetal in rituals of the UDV. They were evaluated in terms of mental and general health. Another 15 individuals - who never used Hoasca tea - were studied with the same methods for purposes of comparison (a control group).
The Hoasca Project indicated that the ritual use of the tea in the UDV is safe. Its results motivated the development of new studies, that are currently under way.